How AI Learns from Evolution to Help Design Enzymes
Patterns in natural protein sequences can help models suggest enzyme changes. A review explains the opportunity, the limits of prediction and why experiments matter.
The science of enzymes. The possibilities they create.
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How enzymes work, evolve and assemble—and what their structures reveal.
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Patterns in natural protein sequences can help models suggest enzyme changes. A review explains the opportunity, the limits of prediction and why experiments matter.
An evolutionary comparison suggests that Rubisco has gradually improved its performance in C₃ flowering plants. The findings offer clues for enzyme engineering, but crop-yield gains…
Cells and enzymes depend on one another today. RNA catalysts, chemical networks and protocell experiments offer clues to how that relationship could have begun.
Marine microbes experience temperature swings, not just yearly averages. A study links that thermal history to enzyme properties and the flexibility of bacterial growth.
Researchers redesigned a sea anemone protein to break down tiny PET particles. The 2023 laboratory study points towards possible water-treatment applications, with important limits.
A 2023 study improved chiral alcohol synthesis by engineering enzymes inside protein cages. The results show why an enzyme's surroundings can change which mutations help.